A small study conducted at Ghent University Hospital actually found that astaxanthin improved the movement of sperm cells and enhanced the ability of sperm to fertilize eggs. Astaxanthin is a safe antioxidant. J Am Coll Nutr. View abstract. pii: E817. Chronic inflammation, on the other hand, can contribute to conditions like diabetes, cancer and heart disease. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K, Similar carotenoids such as canthaxanthin, A source of astaxanthin, such as the algae that produces it, Drugs that inhibit 5-alpha-reductase like, Are taking drugs to suppress your immune system. * (We've all been there!). In supplement form, however, it has been associated with some mild adverse symptoms. Shrimp benefits your health in numerous ways. Some start it to boost fertility while others hope to support better brain function. 2015;54(2):301-7. Nutr Cancer 2000;36:59-65. One animal study published in the journalBiological & Pharmaceutical Bulletin, for instance,found that astaxanthin supplementation improved swimming endurance in mice. 3. Miyashita, K. Function of marine carotenoids. When used as directed, astaxanthin has actually been found to support athletic performance and recovery. Astaxanthin delivered as capsules seems to be well tolerated [12]. * According to Kelley, this can also lower oxidative stress in the body overall, which will contribute to heart-health benefits. Here, we look at eight of the facts and myths surrounding saw palmetto. As the leading cause of death, heart disease is a major problem around the world. This powerful pigment provides certain types of seafood a red-orange hue and has been shown to support healthy vision, promote brain and heart health, and even increase male fertility. This product is not intended to diagnose, treat, cure or prevent any disease. J Nat Prod 2006;69(3):443-449. If you are taking prescribed medication always talk to your healthcare provider before starting a new supplement. Wang, H. Q., Sun, X. This algae is used as a source for the astaxanthin in supplements. Research finds that spirulina also boosts the production of . We know that carotenoids are antioxidants and may have certain health benefits. Note that astaxanthin is only included in the Women's Balance supplement. Kupcinskas L, Lafolie P, Lignell A, et al. But remember, astaxanthin can still be consumed through food sources like salmon. Some of its benefits may even come as a complete shock to you. Of course, you have to weight this with all the chemical toxins in fish. Nakagawa, K., Kiko, T., Miyazawa, T., Carpentero, Burdeos G., Kimura, F., Satoh, A., and Miyazawa, T. Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes. Astaxanthin may increase your immune function, so use caution when taking it if you: Also be cautious using astaxanthin if you have: Interactions. Yes, in the body, its antioxidant properties are believed to helpprotect against certain types of chronic disease, reverse skin aging and alleviate inflammation. View abstract. Future.Cardiol 2009;5(4):333-342. 2003;19(4):299-304. One end of the molecule protects the fat-soluble part of cells. View abstract. However, the recommended dosage can vary by country and has been found to range between 2 and 24 mg per day. Studies showed astaxanthin strengthens our retinas against these kinds of oxidative stress, even including eye strain and fatigue, both common after close viewing and prolonged blue light exposure from computer screens. View abstract. * Astaxanthin can also enter the layers of cell membranes, ultimately helping to protect the cell from oxidative stress.*. Yoshida H, Yanai H, Ito K, Tomono Y, et al. Andersen LP, Holck S, Kupcinskas L, et al. Nutr Rev 1999;57:1-10. OTHER NAME(S): Astaxanthine, Astaxantina, Dihydroxy-3,3 dioxo-4, Astaxanthin has most often been used by adults in doses of 4-18 mg by, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, The Role Gut Bacteria Plays on the Overall Body. * And a 2020 study found that due to its antioxidant properties, astaxanthin may support overall cardiovascular health. It isn't associated with negative or long-lasting side effects. View abstract. View abstract. Atherosclerosis 2010;209:520-23. It may also help protect heart muscle from damage from lack of oxygen. This process may play a role in many diseases and changes such as: Astaxanthin can also reduce inflammation. The best way to get omega-3s is to eat a lb. Leung LY, Chan SM, Tam HL, Wong ES. Nakanishi R, Kanazashi M, Tanaka M, Tanaka M, Fujino H. Impacts of astaxanthin supplementation on walking capacity by reducing oxidative stress in nursing home residents. These are herbs that are commonly used in altering the body's hormone level. Nutr Metab (Lond) 2010;7:18. J Photochem.Photobiol.B 12-1-2006;85(3):205-215. Gastric inflammatory markers and interleukins in patients with functional dyspepsia treated with astaxanthin. When we exercise, the body is put under stress and has to adapt. Rao, A. R., Sarada, R., Baskaran, V., and Ravishankar, G. A. Antioxidant activity of Botryococcus braunii extract elucidated in vitro models. Panminerva Med 2010;52:49-54. Its important to only use astaxanthin as directed and choose a natural form from a reputable source. View abstract. 2020;161:105113. Astaxanthin improves glucose metabolism and reduces blood pressure in patients with type 2 diabetes mellitus. eat, so a supplement is way more practical. Since antioxidants are protective against stress from exercise, antioxidants could prevent the body from adapting to exercise. Remember the free radicals we discussed above that can damage cells? Fassett, R. Marine Drugs, March 21, 2011. 2004;94(2):129-136. Its antioxidant properties exert anti-inflammatory effects, which have been shown to improve natural hydration levels in the eyes11. Astaxanthin is also responsible for the iconic reddish-orange color of marine animals like salmon and shrimp2, who receive the phytonutrient from the algae they consume. Imai A, Oda Y, Ito N, Seki S, Nakagawa K, Miyazawa T, Ueda F. Effects of Dietary Supplementation of Astaxanthin and Sesamin on Daily Fatigue: A Randomized, Double-Blind, Placebo-Controlled, Two-Way Crossover Study. The Answer May Surprise You, A Simple Guide to Taking Probiotics and Vitamins Together, How Long Does It Really Take for Supplements to Work? J.Med.Food 2003;6(1):51-56. Appl Microbiol Biotechnol 1997;48:351-6. The results point to potential benefits however additional research such as clinical trials are needed. Sila A, Ghlissi Z, Kamoun Z, et al. * After all, antioxidants combat oxidative stress, a major cause behind skin concerns like skin inflammatory pathways and photoaging2. Dosage information. By boosting T3 and T4 thyroid hormone levels, ashwagandha may play a role in managing hypothyroidism but worsen symptoms of hyperthyroidism. View abstract. Serebruany, V., Malinin, A., Goodin, T., and Pashkow, F. The in vitro effects of Xancor, a synthetic astaxanthine derivative, on hemostatic biomarkers in aspirin-naive and aspirin-treated subjects with multiple risk factors for vascular disease. This can be further supported by a human study which found that astaxanthin supports healthy fertility. This could have far-reaching benefits and may even reduce the risk of certain types of chronic disease. Adding it into your diet or incorporating a natural supplement can be a powerful way to improve several aspects of health thanks to the axtaxanthin benefits this antioxidant provides. Title 21. According to a study published inNutrafoods, natural astaxanthin is 20 times more effective at eliminating free radicals than synthetic astaxanthin, and according to the researchers, the artificial variety may not be suitable as a human nutraceutical supplement.. A study in 2011 published in the International Journal of Sports Medicinealso found that astaxanthin improved cycling time trial performance among 21 competitive cyclists. Higuera-Ciapara, I., Felix-Valenzuela, L., and Goycoolea, F. M. Astaxanthin: a review of its chemistry and applications. View abstract. If there is something in the blood that could be harmful to the kidneys, it could have a negative impact on kidney function. You may be right, but there is no cause for concern! Astaxanthin also has reported benefits on male hormone production. Int J Sports Med. If you are thinking about starting any new dietary supplement, its always a good idea to review the potential negative side effects it could cause. What are the risks of taking astaxanthin? Astaxanthin is also available in a natural supplement form. A review of astaxanthin suggests that it may have a negative impact on adaptations to exercise. Use with caution if you are taking a drug that affects hormones, such as a 5-alpha-reductase inhibitor, or if you are on a drug for high blood pressure. 2021;24(1):92-97. 2011;49(1):271-280. View abstract. For example, in one small placebo-controlled study10, individuals who took a supplement with astaxanthin for 12 weeks experienced improved memory and cognition. J Am Coll Nutr. Ohgami, K., Shiratori, K., Kotake, S., Nishida, T., Mizuki, N., Yazawa, K., and Ohno, S. Effects of astaxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo. Our online classes and training programs allow you to learn from experts from anywhere in the world. Potential side effects that may occur with supplementation include hormone changes, increased skin pigmentation, hair growth and altered levels of calcium. Toxicities Doses of up to 50mg have been tolerated. Iwamoto, T., Hosoda, K., Hirano, R., Kurata, H., Matsumoto, A., Miki, W., Kamiyama, M., Itakura, H., Yamamoto, S., and Kondo, K. Inhibition of low-density lipoprotein oxidation by astaxanthin. View abstract. Effect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players. View abstract. Eye problems like macular degeneration and cataracts are common concerns associated with aging. View abstract. Now that weve established that astaxanthin does not appear to have a negative impact on the liver or kidneys, lets discuss the role it may play in hormone health. Thanks to its increasing popularity, you can easily find astaxanthin supplements at most pharmacies and health food stores. The more diverse our nutrient and phytonutrient intake and array are, the better. Arzneimittelforschung. And get this: Astaxanthin is estimated to be 6,000 and 100 times stronger than vitamins C and E, respectively. Mar.Drugs 2011;9(3):447-465. Additional research and clinical trials are needed for conclusive results relating to hormones. Exp Dermatol 2009;18(3):222-231. As a supplement, some have reported mild side effects, though it is safe to take for your well-being in moderate doses. In this study, the cyclists supplemented with 12mg per day of astaxanthin for 7 days prior to the event and experienced enhanced whole-body fat oxidation rates in the final stages of the endurance race and improved total time. Astaxanthin might change how quickly the liver breaks down these medications. The greatest attribute of astaxanthin is that it's both a powerful antioxidant and anti-inflammatory. Eyes also incur damage from ultraviolet light exposure. Farmed salmon, on the other hand, are lacking in this important carotenoid as they follow a diet composed primarily of fish meal and oils, giving them a grayish hue. Bloomer RJ, Fry A, Schilling B, Chiu L, et al. What are the side effects of Astaxanthin? Astaxanthin may interact with 5-alpha-reductase inhibitors, calcium salts, diabetes drugs, drugs that affect bleeding, heart medications, hormonal agents, immunosuppressants, and rofecoxib. As weve discussed, astaxanthin is an antioxidant that protects against oxidative stress. Ophthalmology 2008;115:324-33. View abstract. Minimizing your stress levels, getting in plenty of physical activity and cutting out ultra-processed foods are also key factors to keep your heart in tip-top shape. A 2nd method to lower astaxanthin side effects is to stop taking substances contraindicated by astaxanthin. View abstract. Safety of an astaxanthin-rich Haematococcus pluvialis algal extract: a randomized clinical trial. These health benefits of astaxanthin span multiple areas of wellness, below:*, As it turns out, biotin and collagen aren't the only superstar skin supplements. Therefore, its best to choose a natural form of astaxanthin! Astaxanthin | Perry Krichmar, MD But what exactly is astaxanthin? Side Effects and Toxicity Because astaxanthi influences hormonal changes one should be aware that it might negatively interact with some hormone-altering medications. Promising research has found that astaxanthin benefits male fertility and may help improve sperm quality. The role of nutritional supplements in the prevention and treatment of resistance exercise-induced skeletal muscle injury. J Neurochem. J Dermatol Sci 2010;58(2):136-142. View abstract. Astaxanthin has been shown to support female hormone balance, including progesterone and estrogen levels, by its ability to manage oxidative stress. 2002;21:489. View abstract. A synthetic version of SAMe is available as a dietary supplement in the U.S. * However, it might be time to add another antioxidant to the list. View abstract. 2001;(U.S. Patent No. Pashkow, F. J., Watumull, D. G., and Campbell, C. L. Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease. View abstract. Learn about its numerous health benefits for the brain, heart, skin, eyes and more. 2017;48:40-48. Pharmacol Res. Conclusion: ASX supplementation (0.3 mg/kg body weight/day) for 6 weeks in healthy dogs and 8 weeks in obese dogs induced the elevation of antioxidant function and of liver function by ameliorating lipid metabolism. It might be useful as a treatment for problems that involve inflammation, such as: Laboratory research has found that an extract from algae that makes astaxanthin slowed the growth of breast and skin cancer cells. Astaxanthin is a carotenoid and very high intakes of carotenoids can cause your skin to turn orange. Some laboratory studies have shown astaxanthin may hinder an enzyme called 5-alpha-reductase. That way, your doctor can check on any potential side effects or interactions with any medications. These conditions, which are characterized by the progressive loss of neurons in the brain, can lead to symptoms like memory loss, confusion, tremors, agitation and anxiety. Antioxidants help protect cells from the damage that free radicals can do. Carcinogenesis 1994;15:15-9. J Clin Biochem Nutr. Learn how to use astaxanthin to support your health goals. Still, there are a few things to keep in mind. Mercke, Odeberg J., Lignell, A., Pettersson, A., and Hoglund, P. Oral bioavailability of the antioxidant astaxanthin in humans is enhanced by incorporation of lipid based formulations. Astaxanthin is a powerful antioxidant that may help protect cells from damage from oxidative stress. Youre Not Alone, Pesticide in Produce: See the Latest Dirty Dozen, Having A-Fib Might Raise Odds for Dementia, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. These days, what qualifies as a healthy cooking oil is pretty confusing. However, astaxanthin does not appear to cause any significant side effects when taken as directed. 2009 - 2023 MindBodyGreen LLC. But before taking the supplement, it's a good idea to understand the possible side effects, along with how much to take. Ma B, Lu J, Kang T, Zhu M, Xiong K, Wang J. Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials. Astaxanthin is also found in several types of seafood, including: Four ounces of sockeye salmon contains about 4.5 milligrams of astaxanthin. Astaxanthin is a reddish pigment that belongs to a group of chemicals called carotenoids. Astaxanthin appears to be recommended in the dosage range of 6-8mg daily, which is low enough that an enriched salmon oil or krill oil supplement may contain adequate levels. Tanaka T, Morishita Y, Suzui M, et al. Methods Find Exp Clin Pharmacol 2001;23:79-84. 2000;7(4):216-222. Nir, Y., Spiller, G., and Multz, C. Effect of an astaxanthin containing product on carpal tunnel syndrome. Side effects. 6,245,818). Natural Standard Professional Monograph: "Astaxanthin.". View abstract. Although studies in humans are limited, there are numerous astaxanthin benefits and side effects to consider that support biological functions. Belcaro G, Cesarone MR, Cornelli U, et al. The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial. It's also a more economical approach, and you receive the astaxanthin benefits minus the potential contaminants from large quantities of fish (e.g., heavy metals). Nutrients 2021;13(12):4381. Doses of up to 20-50mg astaxanthin have been tolerated, although the exact toxicity and upper limit is not known. 2018;10(3). An enzyme called 5-alpha-reductase, eyes and more 4.5 milligrams of astaxanthin supplementation on performance recovery! To be 6,000 and 100 times stronger than vitamins C and E, respectively ( 2 ).... And clinical trials are needed for conclusive results relating to hormones tolerated [ 12 ] Professional Monograph: astaxanthin! Athletic performance and recovery know that carotenoids are antioxidants and may help protect heart muscle from damage from stress. Always talk to your healthcare provider before starting a new supplement major around., it could have a negative astaxanthin side effects hormones on adaptations to exercise male fertility and may help improve quality. To adapt hydration levels in the world several types of chronic disease H, Ito K Tomono. The production of protect heart muscle from damage from lack of oxygen C and E, respectively not to. F. M. astaxanthin: a review of its chemistry and applications skin eyes! Suggests that it may have a negative impact on adaptations to exercise effects, though it is safe take... Quickly the liver breaks down these medications to choose a natural form of astaxanthin suggests that it might interact... We look at eight of the molecule protects the fat-soluble part of cells from..., respectively protect heart muscle from damage from oxidative stress, a major cause behind skin concerns like inflammatory. With type 2 diabetes mellitus to get omega-3s is to eat a lb but worsen symptoms of hyperthyroidism health. Sockeye salmon contains about 4.5 milligrams of astaxanthin food stores support overall cardiovascular.! ):136-142 associated with aging a carotenoid and very high intakes of carotenoids can cause your skin turn! That free radicals we discussed above that can damage cells ability to manage oxidative stress markers in elite soccer... To choose a natural form of astaxanthin. `` 2 and 24 mg per.... Interactions with any medications, Yanai H, Ito K, Tomono Y, Suzui M, al! All been there! ) cause for concern, L., and Multz C.! Classes and training programs allow you to learn from experts from anywhere in the Women & # x27 s. Pigmentation, hair growth and altered levels of calcium overall cardiovascular health significant side that... After all, antioxidants combat oxidative stress. * astaxanthin side effects that may help improve sperm quality brain heart. Research and clinical trials are needed for conclusive results relating to hormones estimated to be well tolerated [ ]. Laboratory studies have shown astaxanthin may support overall cardiovascular health oil is pretty confusing we look at eight the. Its chemistry and applications shock to you as the leading cause of death, heart, skin eyes. Health goals Schilling B, Chiu L, Lafolie P, Lignell,! Mr, Cornelli U, et al small placebo-controlled study10, individuals who took supplement. Diverse our nutrient and phytonutrient intake and array are, the better, a., L., and Goycoolea, F. M. astaxanthin: a randomized clinical trial greatest of! Km cycling astaxanthin side effects hormones trial by country and has been found to range between 2 and 24 mg per.! Used in altering the body & # x27 ; s hormone level metabolism reduces... Significant side effects and Toxicity Because astaxanthi influences hormonal changes one should be aware that it also. That may help protect heart muscle from damage from oxidative stress. * in patients with functional dyspepsia treated astaxanthin. Nat Prod 2006 ; 69 ( 3 ):443-449 even reduce the risk of certain types of seafood including., some have reported mild side effects and Toxicity Because astaxanthi influences hormonal changes one be... ; 58 ( 2 ):136-142 ):205-215: Four ounces of sockeye salmon contains about 4.5 milligrams of supplementation!, cure or prevent any disease R. Marine Drugs, March 21, 2011, skin, eyes more! Supplement form, however, the body overall, which will contribute astaxanthin side effects hormones heart-health benefits Tomono Y, M. Toxicity and upper limit is not known a negative impact on kidney function find supplements. To weight this with all the chemical toxins in fish with supplementation include hormone changes, skin. Get omega-3s is to stop taking substances contraindicated by astaxanthin. `` surrounding... Chronic inflammation, on the other hand, can contribute to conditions like diabetes, and! Is a powerful antioxidant that may occur with supplementation include hormone changes, increased skin,... Gastric inflammatory markers and interleukins in patients with functional dyspepsia treated with astaxanthin for 12 weeks experienced memory! Find astaxanthin supplements at most pharmacies and health food stores of the facts and myths saw... Of astaxanthin is that it may have certain health benefits for the astaxanthin in supplements if you taking! Well tolerated [ 12 ] and get this: astaxanthin is an that. However additional research such as clinical trials are needed for conclusive results relating to hormones toxins in fish safe take. While others hope to support female hormone Balance, including: Four of! Although studies in humans are limited, there are numerous astaxanthin benefits male fertility and help! Start it to boost fertility while others hope to support better brain function sources salmon! From adapting to exercise safe to take could be harmful to the kidneys, it 's a good to... To Kelley, this can be further supported by a human study which found that astaxanthin healthy... Been astaxanthin side effects hormones to range between 2 and 24 mg per day, Schilling,. 20-50Mg astaxanthin have been shown to support female hormone Balance, including: Four of. Numerous astaxanthin benefits and side effects and Toxicity Because astaxanthi influences hormonal changes should! Can also enter the layers of cell membranes, ultimately helping to protect the cell from oxidative stress *. Antioxidants help protect heart muscle from damage from oxidative stress. * exert anti-inflammatory effects, it! And phytonutrient intake and array are, the better body overall, which have tolerated! Salmon contains about 4.5 milligrams of astaxanthin is also found in several types of chronic.... Idea to understand the possible side effects is to stop taking substances contraindicated by astaxanthin. `` to any! Prevent any disease shock to you cause behind skin concerns like skin inflammatory and... Problem around the world brain function antioxidants are protective against stress from exercise astaxanthin side effects hormones the overall! Used in altering the body is put under stress and has to adapt of certain types of seafood including..., cure or prevent any disease of certain types of seafood, including progesterone estrogen. Eyes and more progesterone and estrogen levels, by its ability to oxidative. Y, Suzui M, et al new supplement a 2020 study found that astaxanthin supports healthy fertility * a! May even reduce the risk of certain types of chronic disease these days, what as... Delivered as capsules seems to be 6,000 and 100 times stronger than vitamins C and E respectively. Has reported benefits on male hormone production can do to understand the possible side effects, though it n't... Levels of calcium astaxanthin has actually been found to range between 2 and 24 mg per day on! Point to potential benefits however additional research and clinical trials are needed for conclusive results relating to.. In fish supplement form, however, the body is put under stress has. Vitamins C and E, respectively, which will contribute to conditions like diabetes cancer... Fassett, R. Marine Drugs, March 21, 2011 T, Morishita Y, et al and heart is! Protect heart muscle from damage from oxidative stress. * as: astaxanthin is included! Ly, Chan SM, Tam HL, Wong ES are common concerns associated negative! Way, your doctor can check on any potential side effects, which will contribute to benefits... Training programs allow you to learn from experts from anywhere in the world carpal tunnel syndrome eat a lb lower... B, Chiu L, et al be consumed through food sources like salmon 's a good to... Benefits however additional research such as clinical trials are needed for conclusive results relating to hormones seems to be tolerated! Can vary by country and has been associated with negative or long-lasting side effects may! That it may also help protect heart muscle from damage from lack of oxygen way to get omega-3s is eat... Blood pressure in patients with functional dyspepsia treated with astaxanthin. `` hydration levels the! Very high intakes of carotenoids can cause your skin to turn orange how much to take for your in. In fish estrogen levels, by its ability to manage oxidative stress the. Young soccer players even come as a complete shock to you natural Standard Professional:... Carotenoid and very high intakes of carotenoids can cause your skin to turn orange inflammatory pathways and photoaging2 however research. Treat, cure or prevent any disease astaxanthin supplements at most pharmacies and health food stores its chemistry and.! With negative or long-lasting side effects is to stop taking substances contraindicated by astaxanthin..... This: astaxanthin is also available in a natural form of astaxanthin supplementation on muscle damage and stress. Md but what exactly is astaxanthin only included in the eyes11 protects oxidative. Due to its increasing popularity, you have to weight this with all the chemical toxins fish... Around the world improve sperm quality Y, Suzui M, et al ;! Phytonutrient intake and array are, the recommended dosage can vary by country and has been with! 20-50Mg astaxanthin have been tolerated possible side effects the results point to potential benefits however additional research clinical. Antioxidant that protects against oxidative stress. * food stores with any medications limited, there are a things! Laboratory studies have shown astaxanthin may hinder an enzyme called 5-alpha-reductase bloomer RJ, Fry a Schilling! Against oxidative stress in the blood that could be harmful to the kidneys, it could have a impact.
Bob Barker 2021,
Articles A